Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
Indian J Sex Transm Dis
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CASE REPORT
Year : 2016  |  Volume : 37  |  Issue : 2  |  Page : 201-204

Anti-retroviral therapy's miracle in the treatment of Bowen's disease in a human immunodeficiency virus-positive patient: A rare case report


Department of Skin and STD, V.M.K.V. Medical College and Hospitals, Salem, Tamil Nadu, India

Correspondence Address:
Kannan Gopalan
No. 80, Nedunchalai Nagar, Salem - 636 005, Tamil Nadu
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7184.192123

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Bowen's disease (BD) is a form of squamous cell carcinoma in situ often associated with human papillomavirus. Co-infection with human immunodeficiency virus (HIV) is associated with a greater risk of malignancy. We describe a case of BD in a 52-year-old unmarried HIV-positive male who presented with extensive skin lesions of 1-year duration. Histopathology was suggestive of BD. He had been tried with topical imiquimod cream and cryo-therapy for 6 months. We observed no response for these above therapies. He was started on with anti-retroviral therapy (ART) as his CD4 count was 253 cells/mm3. The entire cutaneous lesions completely disappeared within 6 months of ART, which was an interesting incidence.


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