Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
Indian J Sex Transm Dis
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Year : 2009  |  Volume : 30  |  Issue : 1  |  Page : 37-39

Progressive varicella syndrome in the setting of pediatric AIDS: An eye opener

Department of STD, Madurai Medical College, Madurai-625 002, India

Correspondence Address:
Subramania M Adityan
Department of STD, Govt Rajaji Hospital, Madurai
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0253-7184.55481

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Varicella zoster virus (VZV) infections are known to be atypical and severe in immunocompromised patients. An eight-year-old girl presented with extremely painful, atypical skin lesions and features of meningitis and pneumonitis. On investigation, she was found to be human immunodeficiency virus (HIV) infected, with very low CD4 count. A diagnosis of 'progressive varicella syndrome' was made, and the child was started on antiretroviral therapy and IV acyclovir. This resulted in a complete resolution of all the clinical features. However, the skin lesions promptly relapsed when acyclovir was withdrawn. Oral Acyclovir was started, and had to be continued to keep the disease under control.

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