Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
Indian J Sex Transm Dis
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REVIEW ARTICLE
Year : 2014  |  Volume : 35  |  Issue : 1  |  Page : 1-11

Initiation of antiretroviral therapy


Department of Dermatology and Sexually Transmitted Diseases, University College of Medical Sciences and Associated Guru Teg Bahadur Hospital, University of Delhi, Delhi, India

Correspondence Address:
Deepika Pandhi
Department of Dermatology and Sexually Transmitted Diseases, University College of Medical Sciences and Associated Guru Teg Bahadur Hospital, University of Delhi, Delhi 110 095
India
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Source of Support: None, Conflict of Interest: None


DOI: 10.4103/0253-7184.132399

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With the widespread availability of antiretroviral therapy, there is a dramatic decline in HIV related morbidity and mortality in both developed and developing countries. Further, the current antiretroviral drug combinations are safer and the availability of newer monitoring assays and guidelines has vastly improved the patient management. The clinician needs to evaluate several key issues prior to institution of antiretroviral regimen including the correct stage of starting the treatment and the kind of regimen to initiate. In addition to various disease related factors, it is also critical to assess the patient's general condition including nutritional status, presence of co-morbidities and mental preparedness prior to starting the therapy. The patients need to develop an overall understanding of the treatment and its benefits and the importance of lifelong adherence to the drugs. The presence of special situations like pediatric age, older patients, pregnancy, lactation and presence of opportunistic infections also require modification of the therapy. This review briefly summarizes issues relevant to the clinician prior to the initiation of antiretroviral therapy.


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