Indian J Sex Transm Dis Indian J Sex Transm Dis
Official Publication of the Indian Association for the Study of Sexually Transmitted Diseases
Indian J Sex Transm Dis
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Year : 2020  |  Volume : 41  |  Issue : 1  |  Page : 113-115

Treatment non-responsiveness in depression following Efavirenz administration

1 Associate Professor, Department of Psychiatry, Government Medical College & Hospital, Chandigarh, India
2 Former Post Graduate Junior Resident, Department of Psychiatry, Government Medical College & Hospital, Chandigarh, India

Correspondence Address:
Dr. Priyanka Bhatia
D/o Mukesh Bhatia, #155, Sec 19(1), HUDA, Sirsa - 125055, Haryana
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ijstd.IJSTD_38_17

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Depression is found as a comorbid condition in patients with human immunodeficiency virus (HIV) infection. Antiretroviral drugs used for the treatment of such infection may result in emergent depression. One such antiretroviral drug is efavirenz (EFV). Induction or exacerbation of depression with EFV has been reported in studies, which resolved after stopping EFV. We report a case of a 23-year-old male patient suffering from HIV for 5 years with treatment nonresponsive depressive symptoms due to EFV which improved after stopping it.

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